In gastrointestinal tract disease, anemia is frequently observed. There were many
reports on operative or clinical findings of upper gastrointestinal treact diseases in
domestic literature but only a few reports on their hematologic findings.
As a preliminary step for studying hematologic changes associated with upper
gastrointestinal tract diseases, we reviewed 1000 patients with gastric or duodenal
disease who had taken gastrofiberscopy from 1972 to 1975 at the Department of Internal
Medicine, Severance Hospital.
Among 1000 cases, 249 were stomach cancer, 235 peptic ulcer, 367 chronic gastritis,
32 erosive gastritis, 27 malignant diseases other than stomach cancer, and 90 normal.
The results obtained are as follow :
1. Hemoglobin and hematocrit of normal group were 14.6gm% and 34.6% in male, and
12.4gm% and 37.1% in female.
2. In stomach cancer, hemoglobin and hematocrit of bleeding group were 9.lgm% and
28.4gm% in male, and 7.0gm% and 22.2% in female; while in non-bleeding cases
11.4gm% and, 34.7% in male, 11.1gm% and 32.2% in female. Cause of anemia was acute
or chronic bleeding in almost cases. There was significant difference in hemoglobin level
between bleeding group and non-bleeding group.
3. In gastric ulcer with bleeding, hemoglobin and hematocrit were 7.9gm% and 23.2%
in male, 6.7gm% and 20.9% in female. In non-bleeding cases with gastric ulcer these
were 13.lgm% and 39.9% in male, 12.9gm1% and 37.4% in female. There was also
significant difference in hemoglobin level between bleeding group and non-bleeding
group.
4. In duodenal ulcer with bleeding, hemoglobin and hematocrit were 9.3gm% and
27.8% in male, 8.9gm% and 26.8% in female. In non-bleeding group of duoderal ulcer, it
was 14.lgm% and 42.6% in male, 13.8gm% and 40.5% in female. Mean hemoglobin of
doudenal ulcer seems to be higher than that of gastric ulcer but there was no statistical
significance.
5. Hemoglobin and hematocrit of chronic superficial gastritis were 13.9gm% and 42.1%
in male, 12.8gm% and 38.1% in female. In chronic atrophic gastritis, hemonglobin and
heulatocrit were 13.1gm% and 38.5% in male, 11.7gm% and 35.4% in female. Mean
hemog1obin of chronic atrophic gastritis seems to be lower than that of chronic
superficia1 gastritis but there was no statistical significance.
6. There were no difference in WBC count in various upper gastrointestinal diseases.
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